A SPECTRUM OF FREE SOFTWARE TOOLS FOR PROCESSING THE VCF VARIANT CALL FORMAT: VCFLIB, BIO-VCF, CYVCF2, HTS-NIM AND SLIVAR.

A spectrum of free software tools for processing the VCF variant call format: vcflib, bio-vcf, cyvcf2, hts-nim and slivar.

Since its introduction in 2011 the variant call format (VCF) has been widely adopted Accessories for processing DNA and RNA variants in practically all population studies-as well as in somatic and germline mutation studies.The VCF format can represent single nucleotide variants, multi-nucleotide variants, insertions and deletions, and simple struct

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Chlamydia pneumoniae is genetically diverse in animals and appears to have crossed the host barrier to humans on (at least) two occasions.

Chlamydia pneumoniae is a common human and animal pathogen associated with a wide range of diseases.Since the first isolation of C.pneumoniae TWAR in 1965, all human isolates have been essentially clonal, Accessories providing little evolutionary insight.To address this gap, we investigated the genetic diversity of 30 isolates from diverse geograph

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